Ingredients in cold medicines replaced

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Pharmaceutical companies increasingly are replacing cold medications containing pseudoephedrine with reformulated products in an effort to keep their remedies on store shelves for the current cold and flu season.

State and local lawmakers in the past two years have begun restricting sales of over-the-counter drugs containing pseudoephedrine, a popular nasal decongestant, because the ingredient can be used to make the illegal narcotic methamphetamine.

In response, Procter & Gamble Co. in November started selling a reformulated version of its Vicks NyQuil syrup and DayQuil and NyQuil liquid caps, replacing pseudoephedrine with acetaminophen and dextromethorphan.

The Cincinnati consumer-products company plans to phase out pseudoephedrine from its cold medicines by 2007, said spokesman Ashoke Mitra, who would not disclose any sales numbers.

"We still believe pseudoephedrine is a safe product," he said.

McNeil Consumer & Specialty Pharmaceuticals, a division of New Brunswick, N.J., health products company Johnson & Johnson, is reformulating its Tylenol Cold & Flu products.

The company for the past year has been eliminating pseudoephedrine for "a wide variety of ingredients," said spokeswoman Kathy Fallon. She would not say whether sales of pseudoephedrine cold medicines have been affected this flu season.

No date is set for when the reformulated products will reach store shelves, she said.

So far, at least 37 states have restricted consumer access to the medications, which has included putting them behind pharmacy or customer service counters at stores, according to the National Conference of State Legislatures.

Additionally, retailers such as Wal-Mart Stores Inc., Target Corp., CVS Corp., Rite Aid Corp., Giant Food LLC and Safeway Inc., have begun limiting access to or have removed them.