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Days later, news reports said that the DCCC was including both New Hampshire races and a Massachusetts race in a $49 million plan to reserve TV ad time in the final weeks of the campaign season.

In the other New Hampshire race for the House, Republicans are optimistic that former Rep. Charlie Bass has a good shot to win the open seat of Rep. Paul W. Hodes, a Democrat who is running for Senate.

They point to Mr. Bass’ strong name recognition as well as his support for lower taxes and a balanced federal budget. In addition, Democrats are worried that the increasingly negative tone of the primary battle between Ann Kuster and Katrina Swett may hurt their chances to unify by November.

The New England states were GOP strongholds for generations. Maine and Vermont were the only holdouts in President Franklin D. Roosevelt’s 1936 re-election landslide. But the transformation began in the late 1960s with the growth of colleges and universities across the region that produced a liberal class of lawyers, professors, bankers and other professionals, while the center of power within the GOP shifted to Southern and Western states.

“You began to see the dominance of the university world,” said Dennis Hale, a Boston College associate professor of political science. “More and more voters became Democrats.”

New England Republicans say it will take a few election cycles to build up a bench of candidates who can raise the funds and assemble the staffs to make credible runs for higher office.

“I wish we did have a strong farm team way back when to prepare people, Massachusetts GOP Chairwoman Jennifer Nassour recently told the Boston Globe. “In another two, four, six years, you will see strong candidates ready to run for higher office.

Still, Mr. Hale and Mr. Mazzola see a sign of hope in Mr. Brown’s improbable win against the heavily favored Democratic candidate, state Attorney General Martha Coakley.

“Voters didn’t believe they could make change,” Mr. Mazzola said. “Scott Brown proved that wrong.”

Indeed, Mr. Bass is appealing to conservatives and “tea party” activists who were key to Mr. Browns victory.

Mr. Bass and Mr. Guinta are among nine Republicans whom the NRCC has brought into its “Young Guns” program, which gives advice and other support to candidates considered to have strong shots at victory. Four are from Connecticut and three are from Massachusetts, including state lawmaker Jeffrey Perry and former state Treasurer Joe Malone. Both are running in the 10th Congressional District, which includes the Cape Cod family estate where Kennedy lived and where Mr. Brown won 60 percent of the vote in the special election.

Mr. Perry, who also is courting tea party activists, was recently elevated to the Young Guns’ second tier, but none of the nine has reached the top tier. Mr. Mazzola said that situation is largely because of the late primaries. The Massachusetts primary, like New Hampshire’s, is Sept. 14.

Beyond New Hampshire, the Massachusetts 10th District is the only one in which Republicans even have a long shot, according the Cook Report. Seven-term Rep. Bill Delahunt is retiring, and forecasters say Democrats are favored to hold the seat.

New England’s other open House seat is that of retiring Rep. Patrick J. Kennedy, Rhode Island Democrat, where the likely GOP candidate will be John Loughlin.

Like Mr. Brown, Mr. Loughlin is a state lawmaker and National Guard member who opposed Mr. Obama’s health care reform. He is working with the Shawmut Group, the political strategists behind Mr. Brown’s upset win, and has the backing of influential Republicans such as former Massachusetts Gov. Mitt Romney and former New York Mayor Rudolph W. Giuliani.

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