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Carolina (plus 7) at New York Giants

Panthers tend to play very well in Meadowlands against Giants, but Big Blue is officially opening Big Gray _ the New Meadowlands Stadium (until a sponsor claims naming rights to the $1.6 billion venue).

GIANTS, 17-16

Detroit (plus 7) at Chicago

So tempting to go with Lions here against a troubled Bears squad. Detroit’s last road win was in October 2007 _ at Soldier Field.

LIONS, 20-7

Cleveland (plus 1) at Tampa Bay

Not so tempting with the Browns in matchup of coaches on the hot seat.

BUCCANEERS, 10-6

Denver (plus 1 1/2) at Jacksonville

How much action does Tim Tebow get in his hometown in his NFL debut? Not enough to make a difference.

Story Continues →