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The Pirates, who have won six of eight, had lost 17 straight interleague series away from home since taking two of three at Tampa Bay in June 2003.

Karstens (6-4) allowed two runs and five hits in seven innings, improving to 3-0 with a 1.52 ERA in six June starts. He walked one and struck out two.

Solo home runs by J.P. Arencibia and Yunel Escobar were the only blemishes for Karstens, who has allowed five home runs in his past two starts, all solo.

Blue Jays left-hander Brett Cecil (1-3) took the loss in his first major league start since April 20, allowing a season-high six runs and eight hits in 6 1-3 innings. He walked three, one intentional, and struck out six.

Astros 7, Rangers 0

HOUSTON (AP) _ Jason Michaels homered and drove in three runs and Wandy Rodriguez and three relievers combined on a four-hitter as Houston snapped an eight-game home losing streak.

Carlos Lee homered for the second straight day in the fourth inning and Chris Johnson drove in two runs in Houston’s four-run fifth as the Astros won at Minute Maid Park for the first time since June 13.

Michaels drove in a run in the fifth before pushing the lead to 7-0 with his two-run shot to left in the seventh.

Rodriguez (6-4) allowed four hits and struck out four in seven innings. David Carpenter pitched a perfect eighth in his major league debut and Fernando Abad and Mark Melancon combined on a scoreless ninth.

Elvis Andrus had two hits for the Rangers in his return after missing the last four games with a sprained left wrist.

Texas starter Matt Harrison (6-7) yielded seven hits and five runs in six innings.

Yankees 5, Brewers 0

NEW YORK (AP) _ CC Sabathia tied his career high with 13 strikeouts and Mark Teixeira hit his 300th homer to help the New York Yankees finish off June with a season-best five-game winning streak by beating the Milwaukee Brewers.

Sabathia (11-4) won for the eighth time in nine starts. He is tied with Detroit’s Justin Verlander for the major league lead in victories.

In 7 2-3 innings, Sabathia gave up six hits and two walks. Every batter he fanned came on a swinging third strike.

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