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In the U.S., the Food and Drug Administration advises women to switch from ACE inhibitors to other drugs once they are pregnant, but there is no warning against using them, as there is for use in the second and third trimesters of pregnancy.

Scientists aren’t sure why high blood pressure in pregnant women could result in birth defects, but suggest there could be physiological changes in mothers that affect fetal growth.

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Online:

http://www.bmj.com