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The Nobel Prizes date back to 1901 after a will left behind by Swedish dynamite inventor Alfred Nobel, and medicine winners are typically awarded for a specific breakthrough rather than a body of research.

The other award categories include physics, chemistry, literature and peace. The economics award isn’t technically a Nobel and was established by Sweden’s central bank in 1968.

The prizes are handed out every year on Dec. 10, on the anniversary of Nobel’s death in 1896.