FOXBOROUGH, Mass. — Tom Brady threw for 423 yards six days after setting a single-game team record of 517, leading the New England Patriots over the San Diego Chargers 35-21 on Sunday.
Brady had three touchdown passes and tied for the third most yards passing in club history, going 31 of 40 with no interceptions as the Patriots (2-0) scored on each of their four first-half possessions.
The Chargers (1-1) turned the ball over inside the Patriots 35-yard line three times, leading to 17 points. They also were stopped on a fourth-and-goal at the 1.
Saints 30, Bears 13
NEW ORLEANS — Drew Brees threw for three touchdowns, and New Orleans’ defense beat up on Chicago quarterback Jay Cutler. Brees’ scoring strikes included a 79-yarder to Devery Henderson.
Darren Sproles scored on a 12-yard swing pass, and Robert Meachem had a 4-yard TD reception for the Saints (1-1). Cutler passed for 244 yards and a score but was sacked six times and fumbled once as he Bears fell to 1-1.
Lions 48, Chiefs 3
DETROIT — Matthew Stafford threw two of his four touchdown passes to Calvin Johnson, and Detroit (2-0) whipped Kansas City (0-2) for the largest margin of victory in franchise history. The Lions broke their record set with a 44-0 win over the expansion Jacksonville Jaguars in 1995.
Chiefs running back Jamaal Charles was carted off the field midway through the first quarter with a torn ACL.
Cowboys 27, 49ers 24 (OT)
SAN FRANCISCO — Playing with a fractured rib, Tony Romo hit Jesse Holley on a 77-yard completion on the Cowboys’ first play of overtime that set up Dan Bailey’s winning 19-yard field goal, and Dallas rallied to edge San Francisco.
It was an exact reverse of what happened a week earlier: a 27-24 road loss to the Jets after Dallas blew a late 14-point lead.
Bailey kicked a tying 48-yard field goal as time expired in regulation after missing an early 21-yard attempt.
Bills 38, Raiders 35
ORCHARD PARK, N.Y. — Ryan Fitzpatrick threw a 6-yard touchdown pass to David Nelson with 14 seconds left to cap a wild fourth quarter to help Buffalo (2-0) outlast Oakland (1-1).
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