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“I was hitting the ball as well as I could from a compromised position and still felt like I was just hanging on,” he said. “I don’t know that it would have been smart to do that for two more sets. And if somehow you pull a rabbit out of the hat, I don’t think you play in two days. If I’m looking at timelines, I think there’s three weeks or so before I have to play again.”

Hewitt, who turns 31 next month, goes to the third round against Milos Raonic, the big-serving, 21-year-old Canadian. If Hewitt eliminates an opponent who has dropped only two service games this year, he could face defending champion Novak Djokovic in the fourth round. Djokovic, who won three of the four major titles last year, kept getting better in his 6-3, 6-2, 6-1 win over Santiago Giraldo.

Fourth-seeded Andy Murray, who lost to Djokovic in last year’s Australian final, ousted Edouard Roger-Vasselin of France 6-1, 6-4, 6-4. No. 5 David Ferrer beat American Ryan Sweeting 6-7 (4), 6-2, 3-6, 6-2, 6-3, and No. 6 Jo-Wilfried Tsonga downed Ricardo Mello of Brazil 7-5, 6-4, 6-4.

Five-time Australian Open champion winner Serena Williams notched her 500th career singles victory Thursday when she beat Barbora Zahlavova Strycova 6-0, 6-4 in the second round.

“Five hundred is a lot of matches to play, let alone to win,” she said, adding that the left ankle she badly sprained two weeks ago wasn’t an issue. “It’s totally fine. It was my good ankle, so I’m good.”

Williams won the Australian Open in 2009 and 2010, but didn’t defend her title in 2011 because she was injured.

No. 2 Petra Kvitova moved into the third round with a 6-2, 2-6, 6-4 win over Carla Suarez Navarro. Maria Sharapova, one of the three former champions in the women’s draw, routed U.S. qualifier Jamie Hampton 6-0, 6-1. No. 7 Vera Zvonareva, a two-time semifinalist at Melbourne Park, No. 9 Marion Bartoli and No. 21 Ana Ivanovic all advanced.