The Golden Eagles were 12-for-26 and dominated inside with a 20-8 advantage inside the paint.
“I think the biggest difference was with us,” John Thompson III said. “I think our decision-making wasn’t as good as it has been and could be … particularly early on. And that led into their success.
“They’re a hard team to guard, they’re a very good offensive team and not too many people have had success guarding them,” he added. “When you play them, we have to make sure we get good shots, and we didn’t do a very smart job of that today.”
Marquette kept the pressure on early in the second half, opening its biggest lead at 48-31 by the 17:55 mark after a Johnson-Odom 3-pointer followed by a Crowder steal and feed to Wilson for a jam.
The Hoyas weren’t quite ready to fold. They nearly halved the deficit over the next 3:15 to 51-43 on Porter’s baseline jumper.
But foul troubles started taking a toll. Hollis Thompson sat for several minutes after collecting his fourth foul. Henry Sims joined him on the bench the 13:42 mark also with four.
Sims then fouled out with 9:33 to play after Marquette’s Johnson-Odom executed a steal.
Georgetown was looking for a season sweep of Marquette after a 73-70 home win on Jan. 4. The Hoyas’ 13 regular season Big East victories are still the most since 2005-06.
Regular-season champion Syracuse had already clinched the No. 1 seed.
Georgetown will play at 2 p.m. Wednesday against the winner of the first round No. 12 vs. 13 seeds. A tournament status update on Saturday morning had Pitt meeting Rutgers for the right to advance and meet the Hoyas.
“We’ve got to do things differently going forward — unlike today,” John Thompson III said.