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No. 7 Tomas Berdych and No. 9 Juan Martin del Potro also made it into the third round.

Azarenka, who took over the No. 1 ranking after winning the Australian Open, easily advanced against Pfizenmaier, a 20-year-old who was making her Grand Slam debut.

In the first round, Azarenka struggled early before winning 12 of the final 14 games to advance. She committed 60 unforced errors in that opening match, but brought that number down to 11 on Wednesday.

“Definitely played much better today,” said Azarenka, who reached the quarterfinals at Roland Garros last year, matching her best performance at the clay-court Grand Slam.

U.S. Open champion Sam Stosur advanced, beating Irina Falconi of the United States 6-1, 6-4. No. 13 Ana Ivanovic, the 2008 French Open champion, also moved on.