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The Obama campaign, meanwhile, pounced on the pick, warning that the Romney-Ryan budget plan would “end Medicare as we know it” and force seniors to pay more for their insurance coverage.

Exit polls from the presidential election suggest the attacks worked, as more of the voters surveyed said they trusted President Obama more when it came to handling Medicare, while Mr. Romney held a slim edge over who is best equipped to handle the deficit and the economy.

In his interview with the Journal Sentinel, Mr. Ryan said Congress is going to have to find a way to work across party lines “because these fiscal issues are getting worse, not better, because of time.”

“I’m very worried about our economy. I’m extremely worried about our debt,” he said, adding, “I do want to be part of the solution.”