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“With our soul, our blood, we will avenge you, our prophet,” they chanted as police fired volleys of tear gas.

Soldiers opened fire to drive away young Muslims in the central Nigerian city of Jos, witnesses and authorities said, and demonstrators in the county’s Muslim north burned a U.S. flag.

Hundreds of hard-line Muslims held peaceful protests against the film throughout Pakistan, shouting slogans and carrying banners criticizing the U.S. and those involved in the film. Police in Islamabad set up barricades and razor wire to prevent protesters from getting to the diplomatic enclave, where the U.S. Embassy and many other foreign missions are located.

About 1,500 protesters in Afghanistan’s eastern city of Jalalabad shouted “Death to America” and urged President Hamid Karzai to cut relations with the U.S.

Additional reporting by Ahmed Al-Haj in Sanaa, Yemen; Bouazza Ben Bouazza in Tunis; Mohamed Osman in Khartoum, Sudan; Elizabeth A. Kennedy in Beirut; and Daniel Estrin in Jerusalem.