- Mandela service sign language interpreter: ‘He made up his own signs’
- Pope Francis named Time’s ‘Person of the Year’
- Ben Affleck: Fundraising for Democrats started to ‘feel gross’
- Vladimir Putin orders military to boost presence in Arctic
- Brooklyn, N.Y.: ‘Lesbian capital’ of the Northeast
- Elian Gonzalez: It’s America’s fault that my mother died
- India top court rules homosexuality is illegal
- Aaron Hernandez, ex-Patriot, on prison life: ‘I’m way less stressed in jail’
- Man pulled from water believed to be disgraced D.C. cop
- Kabul airport hit by suicide bomber who targeted NATO gate
Radiation may up cancer risks in women
Mammograms aimed at finding breast cancer might actually raise the chances of developing it in young women whose genes put them at higher risk for the disease, a study by leading European cancer agencies suggests.
The added radiation from mammograms and other types of tests with chest radiation might be especially harmful to them and an MRI is probably a safer method of screening women younger than 30 who are at high risk because of gene mutations, the authors conclude.
The study can’t prove a link between the radiation and breast cancer, but is one of the biggest ever to look at the issue. The research was published Thursday in the journal BMJ.
“This will raise questions and caution flags about how we treat women with [gene] mutations,” said Dr. Len Lichtenfeld, deputy chief medical officer of the American Cancer Society. He and the society had no role in the research.
Mammograms are most often used in women older than 40, unless they are at high risk, like carrying a mutation of the BRCA1 or BRCA2 gene. Having such a mutation increases the risk of developing cancer fivefold. About one in 400 women has the gene abnormalities, which are more common in Eastern European Jewish populations. Unlike mammograms, an MRI, or magnetic resonance imaging scan, does not involve radiation.
The breast cancer screening tests have been proven to save lives and are clearly beneficial for women 50 and older who have an average risk of breast cancer. Experts are divided about their value in women younger than 50.
Some studies have suggested women with the genetic mutations could be more sensitive to radiation because the genes are involved in fixing DNA problems. If those genes are damaged by radiation, they may not be able to repair DNA properly, raising the cancer risk.
In several European countries including Britain, the Netherlands and Spain, doctors already advise women with BRCA mutations to get MRIs instead of mammograms before age 30. In the U.S., there is no specific advice from a leading task force of government advisers, but the American Cancer Society recommends yearly mammograms and MRIs from age 30 for women with BRCA gene mutations.
In the BMJ study, European researchers followed nearly 2,000 women older than 18 with one of the gene mutations in Britain, France and the Netherlands. Participants reported their previous chest X-rays and mammograms, including the age of their first screening and the number of procedures. About 850 women were later diagnosed with breast cancer. Roughly half of them had X-rays while one third had at least one mammogram, at an average age of 29.
The researchers did not have a breakdown of how many women were exposed to chest radiation before age 30 but estimated that for every 100 30-year-old women with a gene mutation, nine will develop breast cancer by age 40. They projected the number of cases would increase by five if all of them had one mammogram before age 30. But they cautioned their results should be interpreted with caution because most women didn’t have a mammogram before 30.
Researchers found women with a history of chest radiation in their 20s had a 43 percent increased relative risk of breast cancer compared to women who had no chest radiation at that age. Any exposure before age 20 seemed to raise the risk by 62 percent. Radiation after age 30 did not seem to affect breast cancer risk.
The study was paid for by European cancer groups.
By Donald Lambro
Growth spikes are little more than trend-free anomalies
- Teen thugs in DC run wild -- even while wearing GPS ankle bracelets
- New budget accord saves $23 billion -- after $65 billion spending spree
- Obama takes 'selfie' at Mandela's funeral service
- VEGAS RULES: Harry Reid pushed feds to change ruling for casino's big-money foreigners
- CARSON: Why did the founders give us the Second Amendment?
- Gov't Motors: Obama fudges math on auto bailout, $15 billion loss for taxpayers
- Somber duty: U.S. presidents in hot demand at Mandela's memorial
- FITTON: A closer look at the Benghazi lie
- American bourbon now better than Scottish whiskey: U.K.-born expert
- LAMBRO: The dark lining to the silver cloud of Obamanomics
Independent voices from the The Washington Times Communities
Helping the YOUniverse conspire on your behalf.
A column dedicated to discussing politics, national security, civil liberties, and education.
Criticism may not be agreeable, but it is necessary. It fulfills the same function as pain in the human body. It calls attention to an unhealthy state of things.
The “Silver Tsunami” created by aging Baby Boomers is hitting America. Let’s explore how we adjust to it, enjoy it and defy negative expectations about age.
White House pets gone wild!
Let it snow