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Drug-resistant gonorrhea cured in new drug trial
A clinical trial has found two treatment options to cure increasingly drug-resistant modern strains of gonorrhea, but they often have side effects, and federal officials called for more research Monday.
Gonorrhea patients now must get a shot and round of oral antibiotics to kill the sexually transmitted disease, which has developed new defenses against modern drugs.
A clinical trial with 401 gonorrhea patients now has shown that two more anti-gonorrhea regimens — one with a shot and oral antibiotics, and the other with two oral antibiotics — were 100 percent or 99.5 percent effective.
Unfortunately, both regimens had adverse side effects. Roughly a third of the patients experienced nausea, and about a fifth experienced diarrhea.
Gonorrhea is a common disease, with an estimated 800,000 new infections every year in the United States. The sexually transmitted disease has been curable since the 1930s, but it persistently has become drug-resistant and is curable today with an injection of ceftriaxone combined with oral azithromycin or oral doxycycline.
The clinical trial treatments — which will be reported this week at an international STD conference in Austria — studied oral azithromycin combined with either a shot of gentamicin or a round of oral gemifloxicin.
Untreated gonorrhea is associated with painful urination, pelvic pain, ectopic pregnancy and infertility.
© Copyright 2014 The Washington Times, LLC. Click here for reprint permission.
About the Author
Cheryl Wetzstein covers family and social issues as a national reporter for The Washington Times. She has been a reporter for three decades, working in New York City and Washington, D.C. Since joining The Washington Times in 1985, she has been a features writer, environmental and consumer affairs reporter, and assistant business editor.
Beginning in 1994, Mrs. Wetzstein worked exclusively ...
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