Central African Republic President Francois Bozize fled the country Sunday morning after rebels seized control of the capital, Bangui.
The president crossed the Ubangi River into neighboring Democratic Republic of Congo, government officials said.
Reuters reports that at least six South African soldiers were killed in clashes with the rebels.
The Seleka rebel coalition resumed the rebellion this week, vowing to oust the president, whom it accused of breaking a January peace agreement to integrate its fighters into the army, Reuters reports.
"The rebels control the town," presidency spokesman Gaston Mackouzangba said. "I hope there will not be any reprisals."
It is unclear who will replace Mr. Bozize, Reuters reports.
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