49ers, Lions, Saints, Rams win with stars

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At Indianapolis, Andrew Luck’s legs were decisive. The QB ran 19 yards for the winning touchdown. He also was 18 of 23 for 178 yards with two touchdown passes.

Oakland started Terrelle Pryor at quarterback and he made some plays in going 19 of 29 for 217 yards and one TD. He also broke the Raiders’ rushing record for a quarterback with 13 carries for 112 yards, but threw two interceptions in the red zone, the second coming with 25 seconds left.

Chiefs 28, Jaguars 2

At Jacksonville, Andy Reid won his first game as Chiefs coach.

Alex Smith threw two early touchdown passes, Jamaal Charles ran for 77 yards and a touchdown before leaving the game with a quadriceps injury, and Jacksonville advanced past its 36-yard line once.

“You want to win every game you possibly can in the National Football League, that’s what you strive for. You work so stinking hard for every week, then you cherish it,” said Reid, who spent the previous 14 years mostly winning in Philadelphia.

Dolphins 23, Browns 10

At Cleveland, Ryan Tannehill passed for 272 yards and a touchdown, and the Browns fell to 1-14 in Week 1 since 1999. Tannehill, who was given more offensive weapons for his second NFL season, threw a 34-yard TD pass to Brian Hartline in the third quarter and drove the Dolphins to a clinching TD in the fourth.

Cameron Wake had 2 1/2 sacks as the Dolphins sacked Brandon Weeden six times. Weeden threw three interceptions and the Browns never got anything going in coach Rob Chudzinski’s debut.

Rookie Caleb Sturgis kicked three field goals for the Dolphins.

Copyright 2014 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

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