Parker played 10 minutes of the first half and missed his only two shots before departing. The Spurs originally said his return was uncertain, then announced after halftime that he wouldn’t play.
San Antonio led 51-44 at halftime as it tried to eliminate the Portland Trail Blazers.
There was no indication that Parker was injured before leaving the game.
Parker missed 13 games this season, but none due to a hamstring injury.