Five-time champion Serena Williams has lost at the Australian Open for the first time since 2008, struggling with her serve and hitting too many unforced errors during a 6-2, 6-3 setback against No. 56-ranked Ekaterina Makarova of Russia.
Novak Djokovic's third-set wobble against Lleyton Hewitt spoiled a neat statistic. Had the defending champion won in three sets, the top three men would all have reached the quarterfinals without dropping a set.
Returning to Grand Slam tennis after a year away with health problems, Serena Williams opened her Wimbledon title defense Tuesday by beating Aravane Rezai in three sets — then burst into tears on Centre Court.