Looking at the region from the vantage point of Iranian Supreme Leader Ayatollah Ali Khamenei, Mr. Henderson said: "Think of the supreme leader as being a 1960s anti-American. He loathes the U.S. He thinks he has outmaneuvered Washington so is overjoyed. But he may still hate and mistrust Washington so much that he won't endorse an agreement. Even if sanctions are not lifted, he probably judges many of them will collapse. That's his worldview."