- The Washington Times - Tuesday, April 22, 2008

NEW YORK (AP) — Children should be screened for heart problems with an electrocardiogram before getting drugs such as Ritalin to treat hyperactivity and attention-deficit disorder, the American Heart Association recommended yesterday.

Stimulant drugs can increase blood pressure and heart rate. For most children, that isn’t a problem. But in those with heart conditions, it could make them more vulnerable to sudden cardiac arrest — an erratic heartbeat that causes the heart to stop pumping blood through the body — and other heart problems.

About 2.5 million American children and 1.5 American million adults take medication for attention-deficit hyperactivity disorder, or ADHD, according to government estimates. Stimulant drugs, like Ritalin, Adderall and Concerta, help children with ADHD to stay focused and control their behavior.

The medications already carry warnings of possible heart risks in those with heart defects or other heart problems, which some critics said were driven more by concerns of overuse of the drugs than their safety.

The heart organization is now recommending a thorough exam, including a family history and an EKG, before children are put on the drugs to make sure that they don’t have any undiagnosed heart problems.

“We don’t want to keep children who have this from being treated. We want to do it as safely as possible,” said Dr. Victoria Vetter, a pediatric cardiologist at the University of Pennsylvania School of Medicine and head of the committee making the recommendation.

The label warnings were added after a review by the Food and Drug Administration of its databases found reports of 19 sudden deaths in children treated with ADHD drugs and 26 reports of other problems, including strokes and fast heart rates between 1999 and 2003. There also were reports of heart problems in adults; the committee didn’t look at adults.

An EKG can detect abnormal heart rhythms that can lead to sudden cardiac arrest. Children who are already on ADHD drugs should also be tested, Dr. Vetter said. If problems are found, the child should be sent to a pediatric cardiologist. With careful monitoring, Dr. Vetter said, children with heart problems can take the medicines, if needed.

The cost of an EKG varies depending on who does it and the location. For example, the amount that Aetna Inc. pays ranges from $24 to $50. Dr. Vetter said that Children’s Hospital of Philadelphia, where she works, has been doing EKG screening for three years and that it has been covered by insurance.

She said a screening of about 1,100 children found that about 2 percent of them had some kind of heart problem.

“We thought it was reasonable to include the electrocardiogram as a tool for the pediatrician, the psychiatrist, so that this would help identify additional children who have heart disease,” Dr. Vetter said.


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