- Associated Press - Wednesday, November 25, 2015

No. 5 Oklahoma (10-1, 7-1 Big 12, No. 3 CFP) at Oklahoma State (10-1, 7-1, No. 11 CFP), 8 p.m. (ABC)

Line: Oklahoma by 6 ½.

Series Record: Oklahoma leads 84-18-7.

WHAT’S AT STAKE

With Oklahoma’s ascent to No. 3 in the CFP, the Sooners are conference champions and looking like a safe bet to reach the playoff with a win. Oklahoma State can still win its second conference title in five years with a victory. And of course, there’s state pride.

KEY MATCHUP

Oklahoma running back Samaje Perine vs. Oklahoma State’s run defense. Oklahoma State won 38-35 in overtime last year, but Oklahoma was in control before Perine was knocked out of the game with a sprained left ankle in the third quarter. Before that, he ran for 151 yards and two touchdowns, and the Sooners led 28-14. This year, the Sooners have the explosive Joe Mixon in place if something happens to Perine, leaving the Cowboys no better off. Oklahoma ranks 19th nationally in rushing offense; Oklahoma State is 70th in rushing defense.

PLAYERS TO WATCH

Oklahoma: QB Baker Mayfield. The Heisman hopeful had a concussion last Saturday against TCU and sat out the second half. He passed concussion protocol on Sunday, and he is expected to play barring setbacks. He’ll face a front led by DE Emmanuel Ogbah that ranks among the best in the Big 12 at pressuring quarterbacks.

Oklahoma State: QB Mason Rudolph. He got his first career win last year against the Sooners as a true freshman. He has been dynamic this season, passing for 3,591 yards with 21 touchdowns and eight interceptions. He will face his toughest challenge yet - Oklahoma’ defense leads the Big 12 in most categories, including interceptions and sacks.

FACTS & FIGURES

Oklahoma State rushed for eight yards in last week’s loss to Baylor. … Perine needs 50 rushing yards to break into Oklahoma’s career top 10. … Oklahoma coach Bob Stoops has n 8-2 career record against Oklahoma State coach Mike Gundy. … Oklahoma State gave up 700 yards against Baylor, its most since surrendering a school-record 718 against Texas Tech in 2007.

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