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Mr. Ensign has insisted he did nothing illegal.

Senate Minority Leader Mitch McConnell, Kentucky Republican, said Mr. Heller will have an “immediate impact as an advocate for the people of Nevada.”

Mr. Reid also said he welcomes Mr. Heller to the chamber.

“As his responsibilities shift to representing all Nevadans, rather than a single district of our state, I am confident he will work with me and members of both parties to address the serious challenges facing Nevada and the nation,” Mr. Reid said.