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After a series of unsuccessful post-“Mystery Science Theater” pitches in Hollywood, “We just said, ‘Let’s just make something on the Internet and put it out there,’” Mr. Nelson said. “It was essentially just waiting for technology to catch up and be the delivery system.”

For Mr. Hodgson, the success of his show and its more recent iterations is simple: The performances are simply more structured versions of one-way conversations found in most living rooms.

“From the time we are little kids, we grow up watching the screen,” he said. “There’s a certain point where you realize you can say stuff back. That impulse is always going to be there.”

As Hollywood continues to churn out remakes and sequels, movie riffers are confident there will be plenty more material to mock.