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Borrowing costs rose for Spain and Italy, a sign of skepticism that those countries will be able to pay their debts. The yield on Spain’s 10-year government bond rose 0.16 percentage point to 6.58 percent. Last week the yield hit 7.18 percent, the highest since the country started using the euro.

Among other stocks making big moves Monday:

• Teva Pharmaceutical Industries gained 4 percent after the drugmaker said a federal court reaffirmed patents protecting its multiple sclerosis treatment Copaxone. The stock jumped $1.71 to $39.72.

• Chesapeake Energy dropped 8 percent. Reuters reported that the company colluded with a Canadian rival to suppress land prices in areas that were considered rich in oil and natural gas. The stock lost $1.58 to $17.03.

• Pfizer and Bristol-Myers Squibb both sank after federal regulators delayed approving their highly touted blood-thinning drug, Eliquis. Bristol-Myers’s stock dropped 3 percent, or $1.23, to $34.13. Pfizer’s fell 1 percent, or 26 cents, to $22.47.

AP business writers Bernard Condon and Christina Rexrode contributed to this story.