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Mr. Santos over the weekend promised a “180-degree change” in the country’s foreign policy, including resetting ties with Venezuela and Ecuador.

He also pointed to recent military successes in the fight against rebels of the Revolutionary Armed Forces of Colombia (FARC), but he acknowledged there are security “problems that needed to be resolved.”

However, Mr. Santos on Friday did accept the resignation of transportation chief Miguel Penalosa, who has been under investigation for improper contracting procedures.

All 16 Cabinet ministers resigned Wednesday, halfway through Mr. Santos’ presidential term.

He took office in August 2010 with a 70 percent approval rating a year ago, but that figure has plummeted to 45 percent.

From wire dispatches and staff reports