- Associated Press - Wednesday, October 5, 2016

ARIZONA (1-3) at SAN FRANCISCO (1-3)

Thursday, 8:25 p.m. EDT, CBS/NFL Network

OPENING LINE - Cardinals by 5 1/2

RECORD VS. SPREAD - Arizona 1-3, San Francisco 1-3

SERIES RECORD - 49ers lead 29-20

LAST MEETING - Cardinals beat 49ers 19-13, Nov. 29, 2015

LAST WEEK - Cardinals lost to Rams 17-13; 49ers lost to Cowboys 24-17

AP PRO32 RANKING - Cardinals No. 20, 49ers No. 31

CARDINALS OFFENSE - OVERALL (7), RUSH (14), PASS (7).

CARDINALS DEFENSE - OVERALL (8), RUSH (20), PASS (7).

49ERS OFFENSE - OVERALL (28), RUSH (9), PASS (31).

49ERS DEFENSE - OVERALL (26), RUSH (32), PASS (14).

STREAKS, STATS AND NOTES - Cardinals snapped six-game road skid vs. Niners last year and swept season series for first time since 2008. … Arizona QB Carson Palmer out with concussion. Backup Drew Stanton went 5-3 as starter in 2014. … Cardinals RB David Johnson had 124 scrimmage yards last week and has topped 100 yards from scrimmage in four straight. … Arizona WR Larry Fitzgerald has 19 catches for 200 yards, two TDs in last two meetings with San Francisco. … Cardinals LB Chandler Jones has sacks in all four games this season. … 49ers RB Carlos Hyde has five TDs rushing and team has seven this season. … San Francisco QB Blaine Gabbert threw for 318 yards, one TD in last meeting vs. Cardinals. … Niners will be without top defender LB NaVorro Bowman (ruptured Achilles tendon). … San Francisco has allowed only three sacks all season. … 49ers allowed 100-yard rusher in three straight games for first time in single season since 2004. … Fantasy Tip: 49ers WR Jeremy Kerley has been targeted at least six times each game and leads team with 32 targets, leading to 18 catches for 202 yards and one TD.

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Online:

AP NFL website: www.pro32.ap.org and www.twitter.com/AP_NFL

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