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Greinke is 60-67 with a 3.82 ERA in six-plus seasons with the Royals. He sat out most of the 2006 season because of an anxiety disorder and considered quitting baseball.

“A big part of my heart will always pull for Zack,” Moore said. “What he overcame, the success he had here _ to the point it’s not easy to make these types of deals. You would prefer to have him here and sign him long-term but it just wasn’t something we could do.”

Moore expects Greinke to thrive in the National League.

“This guy’s one of the best fielding pitchers in the game,” Moore said. “You can’t bunt on him. He holds runners. He’s a studier. I think he’s going to do terrific.”

The deal is an indication the Brewers are serious about making a playoff run in 2011 _ presumably making it far less likely that the team would trade first baseman Prince Fielder, who can become a free agent at the end of the season and has been the subject of trade speculation.

With the acquisition of Greinke, the Brewers‘ starting staff inches closer to those of Philadelphia and San Francisco in the NL.

But this month’s deals for starting pitchers have cost Milwaukee promising young prospects who might have figured prominently in its future _ and could help the Royals‘ rebuilding effort.

Escobar was the Brewers‘ primary shortstop last season but struggled at the plate, batting .235 with 41 RBIs. Cain played 43 games for the Brewers last season, batting .306 with 13 RBIs.

Jeffress made 10 appearances for the Brewers last season, going 1-0 with a 2.70 ERA. He has been suspended twice under baseball’s drug policy.

Odorizzi was considered the Brewers‘ top minor league pitching prospect.

Moore said the deal made sense for Kansas City because the young players they acquired from Milwaukee fit into what is expected to be a wave of promising young players coming up through their system.

“We expect to be competitive next year,” Moore said. “We’re still working to improve our baseball team.”

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AP Sports Writers Colin Fly in Milwaukee and Doug Tucker in Kansas City, Mo., contributed to this report.