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2009: Jobs explains severe weight loss by saying he has a treatable hormone imbalance and that he will continue to run Apple. Days later he backtracks and announces he will be on medical leave. He returns to work in June. Later it is learned that he received a liver transplant.

2010: Apple sells 15 million iPads, its newest gadget, in nine months, giving rise to a new category of modern touch-screen tablet computers.

Jan. 17, 2011: In a memo to Apple employees, Jobs announces a second medical leave with no set duration. Chief Operating Officer Tim Cook will fill in to run day-to-day operations. Jobs said he will continue as CEO and will be involved in major decisions.

Aug. 24, 2011: Apple announces that Jobs is resigning as CEO. The company says he will be replaced by Cook and that Jobs will stay on as chairman.