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Pakistan responded to the raid by kicking out more than 100 U.S. troops training Pakistanis in counterterrorism operations and reduced the level of intelligence cooperation — something that could make it more difficult for the U.S. to target militants in the country.

One of the primary causes of U.S. frustration with Pakistan is its unwillingness to target Afghan Taliban militants and their allies in the country who launch cross-border attacks against NATO troops in Afghanistan. Pakistan says its troops are stretched too thin by other operations, but many analysts believe the government is reluctant to attack groups with which it has historical ties and could be useful allies in Afghanistan after foreign forces withdraw.

Hussain, the defense professor, said the beginning of the American withdrawal from Afghanistan and Obama’s admission that the U.S. would support reconciliation talks with the Taliban made it even less likely that Pakistan would target militants deemed a threat by Washington.

“If you are talking to the Taliban, then you can’t expect Pakistan to go after them,” Hussain said.

Obama said he would press Pakistan to tackle the militant threat inside the country, but also implied the U.S. would not hesitate to go it alone when its security was endangered.

“For there should be no doubt that so long as I am president, the United States will never tolerate a safe-haven for those who aim to kill us,” Obama said.