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2008: Speculation mounts that Jobs is ill, given weight loss. In September he kicks off an Apple event and says, “The reports of my death are greatly exaggerated,” making a play off a famous Mark Twain quote after Bloomberg News accidentally publishes, then retracts, an obituary that it had prepared in advance.

2009: Jobs explains severe weight loss by saying he has a treatable hormone imbalance and that he will continue to run Apple. Days later he backtracks and announces he will be on medical leave. He returns to work in June. Later it is learned that he received a liver transplant.

2010: Apple sells 15 million of its newest gadget, the iPad, in nine months, giving rise to a new category of modern touch-screen tablet computers.

Jan. 17, 2011: In a memo to Apple employees, Jobs announces a second medical leave with no set duration. Cook again steps in to run day-to-day operations. Jobs retains CEO title and remains involved in major decisions.

Aug. 24, 2011: Apple announces that Jobs is resigning as CEO. Cook takes the CEO title, and Apple names Jobs chairman.

Oct. 5, 2011: Jobs dies at 56. Apple announces his death without giving a specific cause.