GREENSBORO, N.C. — John Henson had 13 points, 10 rebounds and four blocks in his return from a wrist injury, and North Carolina defeated Creighton. Henson had missed the past three games after spraining his left wrist during the Atlantic Coast Conference tournament.
Kendall Marshall added 18 points and 11 assists for the top-seeded Tar Heels (31-5), but he broke a bone in his right wrist during the second half.
Marshall was hurt when he drove to the paint and was knocked to the floor by Ethan Wragge with 10:56 left. Marshall hit 1 of 2 free throws, then left the game briefly before returning and playing about seven more minutes before leaving the game with 1:54 left.
"All we know right now is it's a fracture," Marshall said. "Luckily it's my right hand. If it was my left hand, then we'd probably have some problems. But we'll take it day by day and figure it out."
Coach Roy Williams said team medical staff will confer with Marshall's family Sunday night. Marshall's status for next week's round of 16 in St. Louis is unclear.
Doug McDermott scored 20 points for the eight-seeded Bluejays (29-6), who shot 41 percent and couldn't keep up with the hot-shooting Tar Heels.
Ohio U. 62, South Florida 56
NASHVILLE, Tenn. — Walter Offutt scored 21 points, D.J. Cooper had 19 and No. 13 seed Ohio defeated South Florida to advance to the NCAA tournament's Midwest regional semifinals.
The Bobcats (29-7) will play No. 1 seed North Carolina in their second trip to the regional semifinals.
Ohio trailed by two when Offutt swished a 3-pointer, launching a 10-0 run for the Bobcats. A pair of free throws by Cooper made it 54-46 with 3:28 left.
The Bobcats had a 59-53 lead when Toarlyn Fitzpatrick connected for South Florida's first 3-pointer of the half. But Cooper went 3 for 4 from the line, and the Bulls missed three shots in the final 36 seconds.
Victor Rudd Jr. and Anthony Collins both scored 13 points for the Bulls (22-14).
Michigan State 65, Saint Louis 61
COLUMBUS, Ohio — Draymond Green scored 16 points with 13 rebounds and set up Keith Appling's late 3-pointer, giving top-seeded Michigan State a win over Saint Louis and sending the Spartans to the round of 16 in the West Region.
Michigan State will play No. 4 seed Louisville on Thursday in Phoenix.
Appling added 19 points for the Spartans (29-7), who had to scrap their way past the ninth-seeded Billikens (26-8). Kwamain Mitchell scored 13 and Brian Conklin 11 for Saint Louis, back in the tournament for the first time since 2000.