- Monday, July 14, 2025

The workweek may start with more than a groan — it could be taking a measurable toll on your health, a study from the University of Hong Kong has found. Here’s what you need to know about the Monday stress hormone research:

The University of Hong Kong study

Research reveals lasting impact of Monday anxiety:



  • Older adults who experienced anxiety specifically on Mondays had significantly higher cortisol levels
  • Stress hormone remained elevated in their system one to two months later
  • Study tracked weekly cortisol data from more than 3,500 surveyed adults over 50
  • Research conducted on adults in England

The cortisol increase

Monday anxiety produces measurable hormonal changes:

  • 23% increase in overall cortisol levels among Monday anxiety sufferers
  • Comparison made to people who reported anxiety on other days
  • Cortisol is the body’s primary stress hormone
  • Published findings appear in Journal of Affective Disorders

The health implications

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High cortisol levels pose serious health risks:

  • Consistently high levels can strain the immune system
  • Contributes to long-term health problems such as heart disease and anxiety
  • Health experts warn about sustained cortisol elevation effects
  • Stress hormone impacts extend beyond immediate anxiety response

The retiree finding

Monday spike affects even non-working population:

  • Monday-specific cortisol spike showed up even in retirees
  • Suggests Monday stress extends beyond work-related anxiety
  • Pattern appears regardless of employment status
  • Indicates deeper psychological association with Monday transitions
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The expectation factor

Stanford neuroscientist explains stress anticipation:

  • “Cortisol is not just reactive” according to Robert Sapolsky
  • “Expectation of stress can drive cortisol levels even higher than the stress itself”
  • Mental preparation for Monday increases hormone production
  • Anticipatory stress proves more powerful than actual stressors

The weekend disruption

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Multiple factors contribute to Monday stress:

  • Some of the reaction is mental, but shifts in sleep and routine matter
  • Weekend schedule changes don’t help Monday transition
  • Sleep pattern disruption contributes to cortisol elevation
  • Routine changes compound psychological stress effects

The Columbia expert analysis

Business school professor explains Monday effort:

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  • “There is something effortful about Mondays” says Modupe Akinola
  • Professor at Columbia Business School provided analysis
  • “You have to get up, get dressed, get focused, deal with traffic”
  • “Your body’s stress system is telling you to get ready to battle”

The stress inventory solution

Expert recommends proactive approach:

  • Akinola recommends taking stock of what’s bothering you before week starts
  • “Daily or weekly stress inventory” suggested as management tool
  • Strategy helps “stress move from being background noise to top of mind”
  • “When this happens, you can actually take control”
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Read more:

Monday anxiety triggers lasting stress hormone spike, study finds

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