Niners rout Cardinals, 24-3

Arizona Cardinals quarterback John Skelton spent most of Monday night running for his life in a 24-3 loss to the San Francisco 49ers.

San Francisco 49ers quarterback Alex Smith (11) drops back to pass against the Arizona Cardinals during the first half of an NFL football game, Monday, Oct. 29, 2012, in Glendale, Ariz.  (AP Photo/Ross D. Franklin)

San Francisco 49ers quarterback Alex Smith (11) drops back to pass against the Arizona Cardinals during the first half of an NFL football game, Monday, Oct. 29, 2012, in Glendale, Ariz. (AP Photo/Ross D. Franklin)

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