St. Louis running back Steven Jackson hurt his right leg Sunday while running virtually untouched on a 47-yard touchdown run on the Rams' first offensive play of the season.
Rams quarterback Sam Bradford injured his right index finger when he struck the helmet of an Eagles defender in the fourth quarter. The second-year quarterback wasn't the only signal caller to get injured as Cincinnati rookie Andrew Dalton left his first NFL game with an injured right wrist.
Bradford expects to play in next week's Monday night game at the Giants after X-rays were negative. Jackson, who will undergo an MRI exam Monday, is hopeful the extra day will help him heal.
"I don't see any way I'm not going to be on the field, to be honest with you," Bradford said.
Jackson went straight to the locker room after the scoring run on a simple off-tackle handoff. He returned for a 9-yard carry on the first play of the Rams' next possession before limping off for good.
"It was one of those freak things. I felt a little something there," Jackson said. "I just couldn't be the runner I wanted to be."
St. Louis also lost wide receiver Danny Amendola to a dislocated left elbow in the fourth quarter. In addition, Rams cornerback Ron Bartell left with a stinger and offensive tackle Jason Smith departed with a high left ankle sprain.
"Quite a few of us went down," Jackson said. "Hey, if we're going to have our injuries, let's get them out of the way now, I guess."
Dalton was hit by Browns rookie defensive tackle Phil Taylor on Cincinnati's final offensive play in the first half. He hopes to play next week at Denver.
Pittsburgh linebacker James Harrison left in the fourth quarter with a bruised knee while Ravens rookie corner Jimmy Smith sprained his ankle on a first-quarter kickoff and did not return.
San Diego lost kicker Nate Kaeding on the opening kickoff when he hurt his left knee and missed the rest of the game.
Carolina middle linebacker Jon Beason reinjured his left ankle and was taken to the locker room on a cart in the third quarter of the Panthers' game against the Arizona Cardinals. Beason had been limited in practice this week because of the injury. He fell to the turf with no one around him on a 48-yard touchdown pass from Arizona's Kevin Kolb to Jeff King.
The Colts, who were already without quarterback Peyton Manning (neck), saw linebackers Ernie Sims (knee sprain) and Gary Brackett (shoulder sprain) go down. Houston lost backup running back Derrick Ward to a right ankle injury. Starting back Arian Foster was inactive while recovering from a hamstring injury. Texans starting receiver Kevin Walter injured his left shoulder and will have an MRI on Monday.
The Chicago Bears lost receiver Roy Williams to a groin injury and starting right guard Lance Louis injured his ankle in the first half.
Bills cornerback Terrence McGee left in the first quarter with a hamstring injury and did not return.
'Your papers, please' must never be heard in America
Independent voices from the TWT Communities
News and reviews of notable museums, and exhibits, and art events.
Benghazi: The anatomy of a scandal
Vietnam Memorial adds four names
Cinco de Mayo on the Mall