- The Washington Times - Thursday, November 12, 2026

After Christina Applegate revealed she was misdiagnosed with multiple sclerosis last month, she has been trying to find another reason for her medical woes.

Now, she has a new theory: breast implant poisoning.

The actress, 54, underwent a double mastectomy in 2008 after being diagnosed with breast cancer that same year. Following the procedure, her breasts were replaced with implants.

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“I am way overdue for having them replaced, and I swear over the last five years or whatever I thought, ’What if it’s — seriously — what if they’re leaking and they’re poisoning me?” Ms. Applegate said on her “Messy” podcast Tuesday.

She recounted on the podcast that someone sent her a study about breast implant leakage and poisoning, noting the symptoms seemed similar to MS.

Ms. Applegate told podcast co-host and fellow actress Jamie Lynn Sigler, who has MS, that prior to recording the episode, “I slept … almost the entire day yesterday.”

Aside from fatigue, Ms. Applegate says she has debilitating joint pain.

“It takes me 10 minutes at least to even sit up and get out of my bed, because I just hurt all over,” she said. “And I don’t know if I’m doing that to myself by sleeping too much.”

According to the National Multiple Sclerosis Society, MS is a disease that affects the central nervous system and “disrupts the flow of information within the brain and between the brain and the rest of the body.”

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