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Against a strong pass rush, it becomes more important for a quarterback to spot his open receivers quickly and get rid of the ball early to avoid being sacked.

“Anytime a quarterback is limited in the amount of time that he has to dissect a play or hold on to the ball, then you don’t make as good throws or as good reads,” Brady said.

Ware’s five sacks tie him for fourth in the NFL. The Cowboys (2-2) are tied for eighth in the NFL with 13 sacks. They also have Anthony Spencer with three sacks and Hatcher with two, although Hatcher missed the 34-30 loss to the Detroit Lions with a calf injury before last Sunday’s bye.

“They really get pressure on the quarterback from everybody,” Brady said.

But Ware is the most dangerous.

“They move him around,” Patriots coach Bill Belichick said. “It’s hard to call a play and say, ‘Well, he’s going to be here. This is how we’re going to deal (with) him.’

“You’re not ever sure exactly where he’s going to be, depending on the call they have and what adjustments they make within that call to what you’re doing,” he added. “That’s a big challenge. He’s a heck of a football player. He’s really fast, explosive. … He comes up the middle. He comes outside. He’s a tough matchup problem wherever he is on the field.”

The Patriots have tight end Rob Gronkowski, an excellent blocker, to help. And running back BenJarvus Green-Ellis has improved on his blocking.

Even with that, the Patriots could have a difficult time keeping the strong, speedy Ware away from Brady.

Ware “is one of the best players in the league,” Mankins said. “He’s a defensive end, outside linebacker guy that really gets after the quarterback. He’s got a ton of sacks in his career already and he wreaks a lot of havoc up there. He makes a lot of plays. He makes it tough on the line. He’s a special player.”

And, with his defensive teammates, the Cowboys are a threat to Brady.

“The tackles and tight ends know they’re up for a challenge,” Brady said. “As a quarterback, you don’t just drop back there and hold (the ball) and see how long you can hold it all day because, eventually, they’re going to get there.”